Development of Novel Chimeric Vaccine and Delivery System for Classical Swine Fever Virus
To eliminate the need for a cold chain, DNA vaccine approach was used, in which nanoparticles composed of branched amphiphilic peptide capsules (BAPC) were employed as the DNA delivery agent. The candidate vaccine and the…
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Transdermal Delivery of Branched Amphipathic Peptide Capsule Magnetic (BAPC-MB) in Mice
To test the transdermal delivery capabilities of BAPC-MB, the tails of live mice were dipped in BAPC-MB solution for 1, 5, 15 and 30 minutes. After a 24-hour incubation period, the tissues were harvested for…
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Rat Intestinal Epithelial Cells (IEC-18) Internalize Magnetic Nanobeads (MNBs) Encapsulated Within a Branched Amphipathic Peptide (BAP) Bilayer
To evaluate the effect of BAP encapsulation of magnetic nanobeads on both cellular uptake and cell viability, research was conducted with Branched Amphipathic Peptide Capsule Magnetic Beads (BAPC-MB) and rat intestinal epithelial cells (IEC-18). The…
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Physical Characteristics of 50 and 200 nm Magnetic Beads when Encapsulated with Branched Amphiphilic Peptides (BAP)
Branched Amphipathic Peptide Capsule Magnetic Beads (BAPC-MB) are a new nanoparticle developed for use as in diagnostic platforms. The bases are Maleimide Super Mag Magnetic Beads which are dispersed in 75% ethanol and combined with…
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Two Separate Toxicity Studies Conducted on Apis Melifera (Honey Bees)
Introduction This report outlines two separate toxicity studies conducted on Apis melifera. The first study follows the parameters of the EPA Litmus test and the second study delves deeper into possible BAPC toxicity surpassing the…
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Assessing Branched Amphiphilic Peptide Capsules (BAPC) Delivery of Short Interfering RNA (siRNA) to Mammalian Cells
Objectives Primary: To evaluate knockdown of target protein following antisense siRNA delivery to GFP-CHO cells with BAPC versus current commercial transfection reagents. Secondary: To assess cellular viability through cryopreservation following BAPC treatment. Experimental design Transfection…
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