Peptiplexes – A Review of Therapeutic Applications. In “Nucleic Acid Nanotheranostics: Biomedical Applications

This chapter will discuss cationic polymers containing ɛ-amine groups and immine or amide linkages that are being used as nanocarriers for nonviral gene delivery. We will focus particularly on cationic peptides. Cationic peptides, free or complexed with self-assembling moieties, have been proposed as carriers of small-molecule drugs as well as nucleic acids and are emerging as an alternative tool for gene delivery.