BAPtofect®️-25 is a revolutionary new transfection reagent offering significant advantages over existing products. Comprised of branched amphipathic peptide capsules (BAPC®️), an entirely new class of nanocarrier, the kit overcomes many of the common transfection issues associated with lipid and polymer-based products.
BAPtofect®️-25 is:
- Non-toxic to cells
- Non-immunogenic
- Water soluble
- Able to rapidly transfect cells with a wide variety of nucleic acid and CRISPR components
- Capable of oral and topical administration in in-vivo studies
- Extremely stable in high temperatures
- Biodegradable
- Simple to adhere with nucleic acid and CRISPR components
- Able to rapidly transfect cells
- Demonstrated to protect nucleic acid and CRISPR components from degradation
Transfecting with BAPtofect®️-25 yields improved efficacy and accuracy in your experiments by making the transfection process simple. Simply add nucleic acid or CRISPR components to the pre-formed BAPC®️ and vortex. Complex formation takes place with only a 15-to-20-minute incubation period. Not only will you experience better distribution of your nucleic acid/CRISPR components, but the lack of cytotoxicity results in virtually no cell death. The inherent 20 mV surface charge of BAPC®️ ensures formation of stable, cationic nanoparticle complexes following the loading/adhesion of anionic nucleic acids/CRISPR components to improve cellular uptake.
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