Research Data

To test the transdermal delivery capabilities of BAPC-MB, the tails of live mice were dipped in BAPC-MB solution for 1, 5, 15 and 30 minutes. After a 24-hour incubation period, the tissues were harvested for…

To evaluate the effect of BAP encapsulation of magnetic nanobeads on both cellular uptake and cell viability, research was conducted with Branched Amphipathic Peptide Capsule Magnetic Beads (BAPC-MB) and rat intestinal epithelial cells (IEC-18). The…

Branched Amphipathic Peptide Capsule Magnetic Beads (BAPC-MB) are a new nanoparticle developed for use as in diagnostic platforms. The bases are Maleimide Super Mag Magnetic Beads which are dispersed in 75% ethanol and combined with…

Introduction This report outlines two separate toxicity studies conducted on Apis melifera. The first study follows the parameters of the EPA Litmus test and the second study delves deeper into possible BAPC toxicity surpassing the…

Objectives Primary: To evaluate knockdown of target protein following antisense siRNA delivery to GFP-CHO cells with BAPC versus current commercial transfection reagents. Secondary: To assess cellular viability through cryopreservation following BAPC treatment. Experimental design Transfection…

We provide strong chemical and biophysical evidence that documents that branched amphiphilic peptides, BAPs, known to assemble into spherical nanoassemblies in solution, do assemble as peptide-bilayer-delimited capsules. These nanoassemblies are termed branched amphiphilic peptide capsules…

Development of new and specific insect pest management methods is critical for overcoming pesticide resistance and collateral off-target killings. Gene silencing by feeding dsRNA to insects shows promise in this area. Here we described the…

Branched amphipathic peptide capsules (BAPCs) are biologically derived, bilayer delimited, nanovesicles capable of being coated by or encapsulating a wide variety of solutes. The vesicles and their cargos are readily taken up by cells and…